UBE2L6 Antikörper (N-Term)

Produktnummer ABIN2775687

Produktdetails anti-UBE2L6 Antikörper

Target: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2L6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LLLPDQPPYH LKAFNLRISF PPEYPFKPPM IKFTTKIYHP NVDENGQICL

Homologie: Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 100%, Rat: 85%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against UBE2L6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2L6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 153 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-UBE2L6 Antikörper (ABIN2775687)

Li, Wang, Yang, Li, Qin, Dong, Zhu, Liang, Liang, Han: "The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8." in: Molecular and cellular biochemistry, Vol. 288, Issue 1-2, pp. 151-7, (2006) (PubMed).

Details zu UBE2L6

Target: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Andere Bezeichnung: UBE2L6 (UBE2L6 Produkte)

Synonyme: UBE2L6 antikoerper, RIG-B antikoerper, UBCH8 antikoerper, 2810489I21Rik antikoerper, Ubce8 antikoerper, Ubcm8 antikoerper, UbcM8 antikoerper, ubiquitin conjugating enzyme E2 L6 antikoerper, ubiquitin-conjugating enzyme E2L 6 antikoerper, UBE2L6 antikoerper, Ube2l6 antikoerper

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: MGC40331, RIG-B, UBCH8
Protein Interaction Partner: LONRF1, FBXO31, RBCK1, ARIH2, RBX1, CUL1, SKP1, UBE2L6, UBC, SIAH2, PARK2, RNF144A, UBE3A, RAD23A, ARIH1, SPEN, ISG15, TIMM8A, RAD21, FLT3, ARHGDIA, park, SIAH1, RUNX1, RNF144B, DTX3, RNF19B, TRAF7, TRIM8, RNF122, MUL1, RNF25, RNF150, RNF125, CBLC, TOPORS
Protein Size: 153

Molekulargewicht: 18 kDa

Gen-ID: 9246

NCBI Accession: NM_004223, NP_004214

UniProt: Q8N5D8