CCT4 Antikörper (C-Term)

Produktnummer ABIN2775694

Produktdetails anti-CCT4 Antikörper

Target: CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Saccharomyces cerevisiae, Ziege, Zebrafisch (Danio rerio), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AFADAMEVIP STLAENAGLN PISTVTELRN RHAQGEKTAG INVRKGGISN

Homologie: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CCT4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CCT4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 539 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CCT4 Antikörper (ABIN2775694)

Tarkar, Loges, Slagle, Francis, Dougherty, Tamayo, Shook, Cantino, Schwartz, Jahnke, Olbrich, Werner, Raidt, Pennekamp, Abouhamed, Hjeij, Köhler, Griese, Li, Lemke, Klena, Liu, Gabriel, Tobita et al.: "DYX1C1 is required for axonemal dynein assembly and ciliary motility. ..." in: Nature genetics, Vol. 45, Issue 9, pp. 995-1003, (2013) (PubMed).

Machida, Masutani, Kobayashi, Mikami, Nishino, Miyazawa, Imataka: "Reconstitution of the human chaperonin CCT by co-expression of the eight distinct subunits in mammalian cells." in: Protein expression and purification, Vol. 82, Issue 1, pp. 61-9, (2012) (PubMed).

Details zu CCT4

Target: CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))

Andere Bezeichnung: CCT4 (CCT4 Produkte)

Synonyme: zgc:65789 antikoerper, zgc:77192 antikoerper, Cct4 antikoerper, Dmel\\CG5525 antikoerper, Tcp-1delta antikoerper, Tcp1-delta antikoerper, cct4 antikoerper, MGC89275 antikoerper, CCT4 antikoerper, DKFZp459D1424 antikoerper, LOC100225853 antikoerper, cctd antikoerper, CCT-DELTA antikoerper, Cctd antikoerper, SRB antikoerper, 2610204B21Rik antikoerper, A45 antikoerper, C78323 antikoerper, chaperonin containing TCP1, subunit 4 (delta) antikoerper, chaperonin containing TCP1 subunit 4 antikoerper, chaperonin containing TCP1 subunit 4 L homeolog antikoerper, CG5525 gene product from transcript CG5525-RA antikoerper, chaperonin containing Tcp1, subunit 4 (delta) antikoerper, T-complex protein 1 subunit delta antikoerper, cct4 antikoerper, CCT4 antikoerper, cct4.L antikoerper, CG5525 antikoerper, Cct4 antikoerper, cct-4 antikoerper

Hintergrund: The CCT (chaperonin containing TCP-1) complex functions as a molecular chaperone in the eukaryotic cytosol. CCT4 interacts with human cyclin E which has been implicated in positive control of the G1/S phase transition.
Alias Symbols: SRB, Cctd, CCT-DELTA
Protein Interaction Partner: HUWE1, TP53, FUS, CDC20, NEDD1, TUBG1, LGALS3BP, UBC, STAU1, MDM2, RFWD2, VRK2, PRPF40A, CCT7, USP9X, VARS, CCT3, CCT6A, FBXO6, UBD, FBXW4, CDK9, CDK5, CDK2, CD81, IGSF8, HDAC11, HDAC3, RPS6KA1, ILK, ICAM1, PAN2, VCAM1, PPP5C, PEX14, NOS2, US3, FAM86B2, C
Protein Size: 539

Molekulargewicht: 58 kDa

Gen-ID: 10575

NCBI Accession: NM_006430, NP_006421

UniProt: Q53QP9

Pathways: Embryonic Body Morphogenesis