ZYX Antikörper (Middle Region)

Produktnummer ABIN2775767

Produktdetails anti-ZYX Antikörper

Target: ZYX (Zyxin (ZYX))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZYX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ZYX. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZYX

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 572 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ZYX

Target: ZYX (Zyxin (ZYX))

Andere Bezeichnung: ZYX (ZYX Produkte)

Synonyme: BcDNA:LD06023 antikoerper, CG32018 antikoerper, DLim-1 antikoerper, DmLIM-1 antikoerper, Dmel\\CG32018 antikoerper, Lim102EF antikoerper, ZYX102 antikoerper, Zyx102 antikoerper, Zyx102EF antikoerper, lim antikoerper, zyx102 antikoerper, zyxin antikoerper, zgc:171680 antikoerper, ZYX antikoerper, zyx antikoerper, MGC145270 antikoerper, ESP-2 antikoerper, HED-2 antikoerper, 9530098H06Rik antikoerper, R75157 antikoerper, Zyxin antikoerper, zyxin antikoerper, zyxin S homeolog antikoerper, zyx-1 antikoerper, Zyx antikoerper, zyx antikoerper, ZYX antikoerper, EDI_201420 antikoerper, zyx.S antikoerper

Hintergrund: TRIM50 is an E3 ubiquitin-protein ligase.Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
Alias Symbols: ESP-2, HED-2
Protein Interaction Partner: RTN4IP1, YPEL3, IMP3, PHF21A, PDLIM5, LIN7A, SUMO1, NEDD8, FAM129B, CORO1B, CAND1, PUF60, PAPOLA, NUDC, SEC23B, SEC24C, HIST1H4A, UGP2, TARS, PXN, GART, GARS, APEH, FN1, HIPK3, VCAM1, UBC, UBL7, UFC1, UBXN7, ZC3H7B, TTLL12, FERMT2, TOMM34, AHCYL1, SSSCA1,
Protein Size: 572

Molekulargewicht: 61 kDa

Gen-ID: 7791

NCBI Accession: NM_003461, NP_003452

UniProt: Q15942