TFB2M Antikörper (N-Term)

Produktnummer ABIN2775816

Produktdetails anti-TFB2M Antikörper

Target: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFB2M Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ECNPGPGILT QALLEAGAKV VALESDKTFI PHLESLGKNL DGKLRVIHCD

Homologie: Horse: 100%, Human: 100%, Rabbit: 83%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against TFB2M. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TFB2M

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 396 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TFB2M

Target: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Andere Bezeichnung: TFB2M (TFB2M Produkte)

Synonyme: CG3910 antikoerper, Dmel\\CG3910 antikoerper, TFB2 antikoerper, d-TF2BM antikoerper, d-mtTFB2 antikoerper, TFB2M antikoerper, sb:cb857 antikoerper, hkp1 antikoerper, Hkp1 antikoerper, mtTFB2 antikoerper, mitochondrial transcription factor B2 antikoerper, transcription factor B2, mitochondrial antikoerper, mtTFB2 antikoerper, TFB2M antikoerper, tfb2m antikoerper, Tfb2m antikoerper

Hintergrund: TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Alias Symbols: FLJ22661, FLJ23182, Hkp1, mtTFB2
Protein Interaction Partner: UBC, FBXO6, C1QBP, CUL3, TFB2M, POLRMT, TFAM, PNP,
Protein Size: 396

Molekulargewicht: 45 kDa

Gen-ID: 64216

NCBI Accession: NM_022366, NP_071761

UniProt: Q9H5Q4