KLHL3 Antikörper (N-Term)

Produktnummer ABIN2775874

Produktdetails anti-KLHL3 Antikörper

Target: KLHL3 (Kelch-Like 3 (KLHL3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Kaninchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLHL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: CSPYFCAMFT GDMSESKAKK IEIKDVDGQT LSKLIDYIYT AEIEVTEENV

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Produktmerkmale: This is a rabbit polyclonal antibody against KLHL3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KLHL3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 587 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KLHL3

Target: KLHL3 (Kelch-Like 3 (KLHL3))

Andere Bezeichnung: KLHL3 (KLHL3 Produkte)

Synonyme: 7530408C15Rik antikoerper, AI430941 antikoerper, EG627648 antikoerper, PHA2D antikoerper, RGD1565218 antikoerper, kelch like family member 3 antikoerper, kelch-like 3 antikoerper, kelch-like family member 3 antikoerper, KLHL3 antikoerper, Klhl3 antikoerper

Hintergrund: KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77 % similarity with Drosophila kelch and 89 % similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
Alias Symbols: FLJ40871, KIAA1129, MGC44594, PHA2D
Protein Interaction Partner: WNK4, KLHL12, KLHL3, KEAP1, MORF4L2, CUL3, UBC, C6orf165, WNK3, WNK2, WNK1, RBX1, SLC12A3, ELAVL1, SYNCRIP, SYT2, OPRD1, GNAO1, GNAI1,
Protein Size: 587

Molekulargewicht: 65 kDa

Gen-ID: 26249

NCBI Accession: NM_017415, NP_059111

UniProt: Q9UH77