CAND1 Antikörper (N-Term)

Produktnummer ABIN2775888

Produktdetails anti-CAND1 Antikörper

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAND1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TVIGELPPAS SGSALAANVC KKITGRLTSA IAKQEDVSVQ LEALDIMADM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TIP120A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TIP120A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1230 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CAND1

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Andere Bezeichnung: TIP120A (CAND1 Produkte)

Hintergrund: TIP120A functions as a negative regulator of SCF E3 ubiquitin ligases and may modulate other cullin ligases in a similar fashion.
Alias Symbols: TIP120, TIP120A
Protein Interaction Partner: ISG15, SUMO2, SUMO3, UBE2D1, UBC, UBE2M, CUL1, ASB2, ASB1, PPM1G, PAWR, OSBP, KARS, GARS, CARS, APEH, STAT1, SHMT2, IPO7, SEC23A, JMJD6, HSPA4, TRMT112, ZYX, DCUN1D5, DCUN1D1, SRPK2, UBD, FBXL3, FN1, CFTR, vif, CA9, ECT2, NOTCH1, CUL4A, CUL5, RBX1, ERCC6,
Protein Size: 1230

Molekulargewicht: 136 kDa

Gen-ID: 55832

NCBI Accession: NM_018448, NP_060918

UniProt: Q86VP6

Pathways: Regulation of Actin Filament Polymerization