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Angiomotin Antikörper (N-Term)

AMOT Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Hund, Meerschweinchen, Rind (Kuh), Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2775937
  • Target Alle Angiomotin (AMOT) Antikörper anzeigen
    Angiomotin (AMOT)
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 59
    • 13
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Human, Maus, Ratte, Pferd, Kaninchen, Hund, Meerschweinchen, Rind (Kuh), Zebrafisch (Danio rerio)
    Wirt
    • 49
    • 10
    Kaninchen
    Klonalität
    • 53
    • 6
    Polyklonal
    Konjugat
    • 32
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Angiomotin Antikörper ist unkonjugiert
    Applikation
    • 38
    • 33
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    TANKQLAEKE YEGSEDTRKT ISQLFAKNKE SQREKEKLEA ELATARSTNE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
    Produktmerkmale
    This is a rabbit polyclonal antibody against AMOT. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human AMOT
    Top Product
    Discover our top product AMOT Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 675 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Angiomotin (AMOT)
    Andere Bezeichnung
    AMOT (AMOT Produkte)
    Synonyme
    C81439 antikoerper, CAG-2 antikoerper, D0Kist1 antikoerper, E230009N18Rik antikoerper, Sii6 antikoerper, mKIAA1071 antikoerper, RGD1564027 antikoerper, si:dkey-13f9.6 antikoerper, wu:fj21a07 antikoerper, angiomotin antikoerper, microRNA 4329 antikoerper, AMOT antikoerper, Amot antikoerper, MIR4329 antikoerper, amot antikoerper
    Hintergrund
    AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: KIAA1071
    Protein Interaction Partner: AMOT, C1orf216, WDYHV1, MED4, SNAPC5, PPP2R4, LURAP1, UNC119, LMO4, PIN1, MAGEA4, KRT31, KRT15, FUS, SEPT1, CEP76, HAUS2, LATS2, CEP250, CDKN1A, ACTB, ACTA1, YAP1, SART3, AURKB, MAPK3, BAG3, WWOX, ITCH, LATS1, YWHAG, UBC, PARK2, AMOTL1, SPICE1, MPP7, CNTR
    Protein Size: 675
    Molekulargewicht
    73 kDa
    Gen-ID
    154796
    NCBI Accession
    NM_133265, NP_573572
    UniProt
    Q4VCS5
    Pathways
    Cell-Cell Junction Organization, Regulation of Cell Size
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