TRIOBP Antikörper (Middle Region)

Produktnummer ABIN2775973

Produktdetails anti-TRIOBP Antikörper

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIOBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: QIHTKDAVYT LSAMTSGIRR NWIEALRKTV RPTSAPDVTK LSDSNKENAL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIOBP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIOBP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 431 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIOBP

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Andere Bezeichnung: TRIOBP (TRIOBP Produkte)

Synonyme: tara antikoerper, DFNB28 antikoerper, TARA antikoerper, dJ37E16.4 antikoerper, AI428493 antikoerper, EST478828 antikoerper, Tara antikoerper, mKIAA1662 antikoerper, TRIO and F-actin binding protein antikoerper, TRIO and F-actin-binding protein antikoerper, TRIO and F-actin binding protein L homeolog antikoerper, TRIO and F-actin binding protein-like antikoerper, TRIOBP antikoerper, LOC100354753 antikoerper, triobp.L antikoerper, TRIOBPL antikoerper, Triobp antikoerper

Hintergrund: TRIOBP is a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness.This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio-binding protein also associates with F-actin and stabilizes F-actin structures. Domains contained in this encoded protein are an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
Alias Symbols: DFNB28, FLJ39315, HRIHFB2122, KIAA1662, TARA, dJ37E16.4
Protein Interaction Partner: POLR1C, IKBKG, GTF2H1, PLK1, ELAVL1, VIM, HECTD3, UBC,
Protein Size: 431

Molekulargewicht: 47 kDa

Gen-ID: 11078

NCBI Accession: NM_138632, NP_619538

UniProt: Q9H2D6

Pathways: Regulation of Actin Filament Polymerization