CREM Antikörper (C-Term)

Produktnummer ABIN2776017

Produktdetails anti-CREM Antikörper

Target: CREM (CAMP Responsive Element Modulator (CREM))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Schaf, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CREM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Crem. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Crem

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 357 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CREM

Target: CREM (CAMP Responsive Element Modulator (CREM))

Andere Bezeichnung: Crem (CREM Produkte)

Synonyme: CREM antikoerper, ICER antikoerper, CREM-2 antikoerper, hCREM-2 antikoerper, ICERI antikoerper, Icer antikoerper, cAMP responsive element modulator antikoerper, CREM antikoerper, Crem antikoerper

Hintergrund: Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.
Alias Symbols: Icer
Protein Interaction Partner: Stub1, Ubc,
Protein Size: 357

Molekulargewicht: 39 kDa

Gen-ID: 25620

NCBI Accession: NM_001110860, NP_001104330

UniProt: Q03061

Pathways: Retinoic Acid Receptor Signaling Pathway