RFX6 Antikörper (Middle Region)

Produktnummer ABIN2776023

Produktdetails anti-RFX6 Antikörper

Target: RFX6 (Regulatory Factor X 6 (RFX6))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LGTRGHSKYH YYGIGIKESS AYYHSVYSGK GLTRFSGSKL KNEGGFTRKY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Rfx6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of MOUSE Rfx6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RFX6

Target: RFX6 (Regulatory Factor X 6 (RFX6))

Andere Bezeichnung: Rfx6 (RFX6 Produkte)

Synonyme: MTFS antikoerper, RFXDC1 antikoerper, dJ955L16.1 antikoerper, 4930572O07Rik antikoerper, Rfxdc1 antikoerper, regulatory factor X6 antikoerper, regulatory factor X, 6 antikoerper, RFX6 antikoerper, Rfx6 antikoerper

Hintergrund: Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin. Not required for pancreatic PP (polypeptide-producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes.
Protein Size: 524

Molekulargewicht: 57 kDa

Gen-ID: 320995

Pathways: Carbohydrate Homeostasis