SRY Antikörper (Middle Region)

Produktnummer ABIN404966

Produktdetails anti-SRY Antikörper

Target: SRY (Sex Determining Region Y (SRY))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SEVQLDNRLY RDDCTKATHS RMEHQLGHLP PINAASSPQQ RDRYSHWTKL

Homologie: Human: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SRY. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRY

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 204 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SRY

Target: SRY (Sex Determining Region Y (SRY))

Andere Bezeichnung: SRY (SRY Produkte)

Hintergrund: SRY is an intronless gene that encodes for a transcription factor, which is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor(TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome), translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome), translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TDF, TDY, SRXX1, SRXY1
Protein Interaction Partner: Olig2, Utf1, Tcf12, Sp1, Pou3f3, Pax3, Jun, Hhex, Egr2, Dlx5, Cebpa, WDR5, SMAD3, HDAC3, KPNB1, EP300, Xpo4, ZNF208, SLC9A3R2, AR,
Protein Size: 204

Molekulargewicht: 24 kDa

Gen-ID: 6736

NCBI Accession: NM_003140, NP_003131

UniProt: Q05066