DIDO1 Antikörper (N-Term)

Produktnummer ABIN2776068

Produktdetails anti-DIDO1 Antikörper

Target: DIDO1 (Death Inducer-Obliterator 1 (DIDO1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIDO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ERVEQFLTIA RRRGRRSMPV SLEDSGEPTS CPATDAETAS EGSVESASET

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Yeast: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against DIDO1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DIDO1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 544 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DIDO1

Target: DIDO1 (Death Inducer-Obliterator 1 (DIDO1))

Andere Bezeichnung: DIDO1 (DIDO1 Produkte)

Hintergrund: In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. DIDO1 gene is similar to the mouse gene and therefore is thought to be involved in apoptosis.Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.
Alias Symbols: BYE1, DIO1, DATF1, DIDO2, DIDO3, DIO-1, DATF-1, C20orf158, dJ885L7.8
Protein Interaction Partner: UBC, WWOX, RPA3, RPA2, RPA1, EED, BMI1, HECW2, SRPK2, KCNK4, ARAF, Dlg4, H2AFY, U2AF1, SON, RPL18A, KRT7, APP, PCDHA2, H2AFY2, GNL3, RRS1, SIRT7, SUMO2, WWP2, WWP1, DVL3, SRSF1, HNRNPK,
Protein Size: 544

Molekulargewicht: 59 kDa

Gen-ID: 11083

NCBI Accession: NM_080797, NP_542987

Pathways: Hormone Activity