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KCNN3 Antikörper (C-Term)

KCNN3 Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776146
  • Target Alle KCNN3 Antikörper anzeigen
    KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
    Bindungsspezifität
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 25
    • 17
    • 17
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd
    Wirt
    • 24
    • 1
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCNN3 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 8
    • 6
    • 6
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    ITELNDRSED LEKQIGSLES KLEHLTASFN SLPLLIADTL RQQQQQLLSA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against KCNN3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human KCNN3
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 736 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
    Andere Bezeichnung
    KCNN3 (KCNN3 Produkte)
    Synonyme
    KCa2.3 antikoerper, SK3 antikoerper, SKCA3 antikoerper, hSK3 antikoerper, potassium calcium-activated channel subfamily N member 3 antikoerper, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 antikoerper, Kcnn3 antikoerper, KCNN3 antikoerper
    Hintergrund
    Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
    Alias Symbols: SK3, hSK3, SKCA3, KCa2.3
    Protein Interaction Partner: UBC, RAB5A, DNM2, CAV1, APP, CALM1,
    Protein Size: 736
    Molekulargewicht
    81 kDa
    Gen-ID
    3782
    NCBI Accession
    NM_002249, NP_002240
    UniProt
    Q9UGI6
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