CLCNKA Antikörper (N-Term)

Produktnummer ABIN309765

Produktdetails anti-CLCNKA Antikörper

Target: CLCNKA (Chloride Channel Ka (CLCNKA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLCNKA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MEELVGLREG FSGDPVTLQE LWGPCPHIRR AIQGGLEWLK QKVFRLGEDW

Homologie: Cow: 90%, Human: 100%, Mouse: 85%, Pig: 85%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CLCNKA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CLCNKA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 687 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CLCNKA

Target: CLCNKA (Chloride Channel Ka (CLCNKA))

Andere Bezeichnung: CLCNKA (CLCNKA Produkte)

Hintergrund: CLCNKA is a member of the CLC family of voltage-gated chloride channels. It is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CLCK1, ClC-K1, MGC61490, hClC-Ka
Protein Size: 687

Molekulargewicht: 75 kDa

Gen-ID: 1187

NCBI Accession: NM_004070, NP_004061

UniProt: P51800

Pathways: Response to Water Deprivation