ASIC3 Antikörper (N-Term)

Produktnummer ABIN2776167

Produktdetails anti-ASIC3 Antikörper

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASIC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: VATFLYQVAE RVRYYREFHH QTALDERESH RLIFPAVTLC NINPLRRSRL

Homologie: Cow: 80%, Dog: 80%, Guinea Pig: 80%, Horse: 80%, Human: 100%, Mouse: 87%, Pig: 87%, Rabbit: 87%, Rat: 87%

Produktmerkmale: This is a rabbit polyclonal antibody against ACCN3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACCN3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 531 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ASIC3

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Andere Bezeichnung: ACCN3 (ACCN3 Produkte)

Synonyme: ACCN3 antikoerper, Accn3 antikoerper, DRASIC antikoerper, SLNAC1 antikoerper, TNaC1 antikoerper, AW742291 antikoerper, TNAC1 antikoerper, amiloride-sensitive cation channel 3 antikoerper, acid sensing ion channel subunit 3 antikoerper, acid-sensing (proton-gated) ion channel 3 antikoerper, ACCN3 antikoerper, ASIC3 antikoerper, Asic3 antikoerper

Hintergrund: ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
Alias Symbols: ACCN3, TNaC1, DRASIC, SLNAC1
Protein Interaction Partner: ASIC3, LIN7B, GOPC, INADL, DLG4, MAGI1, ASIC2, STOM, CSNK2A1, PRKACA, STOML1,
Protein Size: 531

Molekulargewicht: 58 kDa

Gen-ID: 9311

NCBI Accession: NM_004769, NP_004760

UniProt: Q9UHC3