KCNK4 Antikörper (N-Term)

Produktnummer ABIN2776270

Produktdetails anti-KCNK4 Antikörper

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MRSTTLLALL ALVLLYLVSG ALVFRALEQP HEQQAQRELG EVREKFLRAH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Pig: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against KCNK4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNK4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 393 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-KCNK4 Antikörper (ABIN2776270)

Bogdan, Fitzgibbon, Woolverton, Bethea, Iyo, Stockmeier, Kyle, Austin: "5-HTTLPR genotype and gender, but not chronic fluoxetine administration, are associated with cortical TREK1 protein expression in rhesus macaques." in: Neuroscience letters, Vol. 503, Issue 2, pp. 83-6, (2011) (PubMed).

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Details zu KCNK4

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Andere Bezeichnung: KCNK4 (KCNK4 Produkte)

Synonyme: K2p4.1 antikoerper, TRAAK antikoerper, TRAAK1 antikoerper, MLZ-622 antikoerper, TRAAKt antikoerper, Tex40 antikoerper, KT4.1 antikoerper, potassium two pore domain channel subfamily K member 4 antikoerper, potassium channel, subfamily K, member 4 antikoerper, KCNK4 antikoerper, Kcnk4 antikoerper

Hintergrund: Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. KCNK4 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. It homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: K2p4.1, TRAAK, TRAAK1
Protein Interaction Partner: DIDO1, RPL14,
Protein Size: 393

Molekulargewicht: 43 kDa

Gen-ID: 50801

NCBI Accession: NM_033310, NP_201567

UniProt: Q9NYG8