CATSPER2 Antikörper (N-Term)

Produktnummer ABIN2776300

Produktdetails anti-CATSPER2 Antikörper

Target: CATSPER2 (Cation Channel, Sperm Associated 2 (CATSPER2))

Bindungsspezifität: N-Term

Reaktivität: Human, Kaninchen, Rind (Kuh), Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CATSPER2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: HLQGLSQAVP RHTIRELLDP SRQKKLVLGD QHQLVRFSIK PQRIEQISHA

Homologie: Cow: 85%, Horse: 92%, Human: 100%, Pig: 92%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CATSPER2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CATSPER2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 414 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CATSPER2 Antikörper (ABIN2776300)

Kawano, Araki, Yoshida, Hibino, Ohnami, Makino, Kanai, Hasuwa, Yoshida, Miyado, Umezawa: "Seminal vesicle protein SVS2 is required for sperm survival in the uterus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 11, pp. 4145-50, (2014) (PubMed).

Details zu CATSPER2

Target: CATSPER2 (Cation Channel, Sperm Associated 2 (CATSPER2))

Andere Bezeichnung: CATSPER2 (CATSPER2 Produkte)

Synonyme: CATSPER2 antikoerper, cation channel, sperm associated 2 antikoerper, cation channel sperm associated 2 antikoerper, CATSPER2 antikoerper, Catsper2 antikoerper

Hintergrund: Calcium ions play a primary role in the regulation of sperm motility. Anti-CATSPER2 belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. A second, closely linked copy of this gene has been identified. Although multiple transcript variants encoding protein isoforms have been characterized, they seem to be only transcribed from this gene. Additional splice variants have been described but their full-length nature has not been determined.
Protein Size: 414

Molekulargewicht: 46 kDa

Gen-ID: 117155

NCBI Accession: NM_172096, NP_742094

UniProt: Q96P54