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PITX2 Antikörper (N-Term)

PITX2 Reaktivität: Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776373
  • Target Alle PITX2 Antikörper anzeigen
    PITX2 (Paired-Like Homeodomain 2 (PITX2))
    Bindungsspezifität
    • 10
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 58
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund
    Wirt
    • 52
    • 5
    • 1
    Kaninchen
    Klonalität
    • 55
    • 3
    Polyklonal
    Konjugat
    • 28
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PITX2 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 38
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    SAVSSSSCHH PQPLAMASVL APGQPRSLDS SKHRLEVHTI SDTSSPEAAE
    Homologie
    Cow: 100%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PITX2. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PITX2
    Top Product
    Discover our top product PITX2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 324 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hatou, Yoshida, Higa, Miyashita, Inagaki, Okano, Tsubota, Shimmura: "Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/?-catenin signaling." in: Stem cells and development, Vol. 22, Issue 5, pp. 828-39, (2013) (PubMed).

  • Target
    PITX2 (Paired-Like Homeodomain 2 (PITX2))
    Andere Bezeichnung
    PITX2 (PITX2 Produkte)
    Synonyme
    ARP1 antikoerper, Brx1 antikoerper, IDG2 antikoerper, IGDS antikoerper, IGDS2 antikoerper, IHG2 antikoerper, IRID2 antikoerper, Otlx2 antikoerper, PTX2 antikoerper, RGS antikoerper, RIEG antikoerper, RIEG1 antikoerper, RS antikoerper, 9430085M16Rik antikoerper, Brx1a antikoerper, Brx1b antikoerper, Munc30 antikoerper, Pitx2a antikoerper, Pitx2b antikoerper, Pitx2c antikoerper, Pitx2cbeta antikoerper, Ptx2 antikoerper, Rieg antikoerper, pitx2a antikoerper, pitx2c antikoerper, zgc:110508 antikoerper, XPtx2b antikoerper, xPtx2 antikoerper, xpitx2 antikoerper, arp1 antikoerper, brx1 antikoerper, idg2 antikoerper, igds antikoerper, igds2 antikoerper, ihg2 antikoerper, irid2 antikoerper, otlx2 antikoerper, pitx2-A antikoerper, ptx2 antikoerper, rgs antikoerper, rieg antikoerper, rieg1 antikoerper, pitx-2 antikoerper, pitx2 antikoerper, paired like homeodomain 2 antikoerper, paired-like homeodomain transcription factor 2 antikoerper, paired-like homeodomain 2 antikoerper, paired like homeodomain 2 S homeolog antikoerper, paired like homeodomain 2 L homeolog antikoerper, PITX2 antikoerper, Pitx2 antikoerper, pitx2 antikoerper, pitx2.S antikoerper, pitx2.L antikoerper
    Hintergrund
    The PITX2 gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. Mutations in PITX2 are associated with Axenfeld-Rieger syndrome (ARS), iridogoniodysgenesis syndrome (IGDS), and sporadic cases of Peters anomaly. This protein is involved in the development of the eye, tooth and abdominal organs. It also acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
    Alias Symbols: RS, RGS, ARP1, Brx1, IDG2, IGDS, IHG2, PTX2, RIEG, IGDS2, IRID2, Otlx2, RIEG1
    Protein Interaction Partner: LEF1, Hoxa1, WDR5, SMAD3, HDAC1, CTNNB1, ZNHIT3, TRIM25, HERC5, PDLIM1, PITX2, PROP1, KAT5, Pou1f1, MSX2,
    Protein Size: 324
    Molekulargewicht
    36 kDa
    Gen-ID
    5308
    NCBI Accession
    NM_000325, NP_000316
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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