EED Antikörper (N-Term)

Produktnummer ABIN2776407

Produktdetails anti-EED Antikörper

Target: EED (Embryonic Ectoderm Development (EED))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EED Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: GDENDDAVSI ESGTNTERPD TPTNTPNAPG RKSWGKGKWK SKKCKYSFKC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against EED. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EED

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 441 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EED Antikörper (ABIN2776407)

Lin, Huang, Chang, Chang, Yen, Lee, Chang, Liu, Chang: "Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2." in: BMC cancer, Vol. 16, pp. 583, (2016) (PubMed).

Rakotobe, Violot, Hong, Gouet, Boulanger: "Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed beta-propeller domain of the HIV-1 cellular interactor EED." in: Virology journal, Vol. 5, pp. 32, (2008) (PubMed).

Details zu EED

Target: EED (Embryonic Ectoderm Development (EED))

Andere Bezeichnung: EED (EED Produkte)

Synonyme: Xeed antikoerper, heed antikoerper, wait1 antikoerper, EED antikoerper, HEED antikoerper, WAIT1 antikoerper, zgc:112509 antikoerper, Xeed-B antikoerper, eed antikoerper, psXEED antikoerper, ENSMUSG00000039373 antikoerper, l(7)5Rn antikoerper, l7Rn5 antikoerper, lusk antikoerper, Xeed-A antikoerper, embryonic ectoderm development antikoerper, embryonic ectoderm development S homeolog antikoerper, microRNA 6755 antikoerper, embryonic ectoderm development L homeolog antikoerper, eed antikoerper, EED antikoerper, eed.S antikoerper, MIR6755 antikoerper, Eed antikoerper, eed.L antikoerper

Hintergrund: EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhance
Alias Symbols: HEED, WAIT1
Protein Interaction Partner: PINK1, BRCA1, ADAM17, EZH2, IMP3, PSPC1, NAT10, PBRM1, RIF1, RBM28, HEATR1, MAGOHB, ARGLU1, MRPL20, NRDE2, CASZ1, BCOR, EXOSC4, LUC7L3, SF3B6, NOP58, SRRT, RAB14, C9orf114, CRNKL1, DDX47, HP1BP3, MYEF2, TRA2A, CPSF1, IGHV3-23, UTP20, PRPF19, ZNF638, RBMX,
Protein Size: 441

Molekulargewicht: 50 kDa

Gen-ID: 8726

NCBI Accession: NM_003797, NP_003788

UniProt: O75530