Nucleolar Protein 6 Antikörper (N-Term)

Produktnummer ABIN2776561

Produktdetails anti-Nucleolar Protein 6 Antikörper

Target: Nucleolar Protein 6 (NOL6)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nucleolar Protein 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SRKRTLAEPP AKGLLQPVKL SRAELYKEPT NEELNRLRET EILFHSSLLR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against NOL6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NOL6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1146 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Nucleolar Protein 6

Target: Nucleolar Protein 6 (NOL6)

Andere Bezeichnung: NOL6 (NOL6 Produkte)

Synonyme: NRAP antikoerper, UTP22 antikoerper, bA311H10.1 antikoerper, nrap antikoerper, utp22 antikoerper, AA410091 antikoerper, Nrap antikoerper, nucleolar protein 6 antikoerper, nucleolar protein 6 L homeolog antikoerper, nucleolar protein family 6 (RNA-associated) antikoerper, NOL6 antikoerper, Nol6 antikoerper, nol6.L antikoerper

Hintergrund: NOL6 is a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
Alias Symbols: FLJ21959, MGC14896, MGC14921, MGC20838, NRAP, UTP22, bA311H10.1
Protein Interaction Partner: UBC, SIAH1, LIN28A, RNF2, BMI1, EED, SIRT7, SUMO2, SUMO1, G3BP1,
Protein Size: 1146

Molekulargewicht: 127 kDa

Gen-ID: 65083

NCBI Accession: NM_022917, NP_075068

UniProt: Q9H6R4