SRSF10 Antikörper (C-Term)

Produktnummer ABIN2776611

Produktdetails anti-SRSF10 Antikörper

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRSF10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: TDSKTHYKSG SRYEKESRKK EPPRSKSQSR SQSRSRSKSR SRSWTSPKSS

Homologie: Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FUSIP1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FUSIP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 262 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SRSF10

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Andere Bezeichnung: FUSIP1 (SRSF10 Produkte)

Synonyme: FUSIP1 antikoerper, SFRS13A antikoerper, FUSIP2 antikoerper, NSSR antikoerper, SFRS13 antikoerper, SRp38 antikoerper, SRrp40 antikoerper, TASR antikoerper, TASR1 antikoerper, TASR2 antikoerper, Fusip1 antikoerper, NSSR1 antikoerper, NSSR2 antikoerper, Nssr antikoerper, Sfrs13a antikoerper, Srsf13a antikoerper, fusip1 antikoerper, fusip2 antikoerper, nssr antikoerper, sfrs13 antikoerper, sfrs13a antikoerper, srp38 antikoerper, srrp40 antikoerper, tasr antikoerper, tasr1 antikoerper, tasr2 antikoerper, serine and arginine rich splicing factor 10 antikoerper, serine/arginine-rich splicing factor 10 antikoerper, serine/arginine-rich splicing factor 10 S homeolog antikoerper, SRSF10 antikoerper, Srsf10 antikoerper, srsf10.S antikoerper

Hintergrund: FUSIP1 is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing.This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.
Alias Symbols: FUSIP2, NSSR, SFRS13, SRp38, SRrp40, TASR, TASR1, TASR2, FUSIP1, SFRS13A
Protein Interaction Partner: STAU1, WWOX, SUZ12, EED, RNF2, EZH2, HECW2, TRA2B, SRSF4, SRSF1, CSNK2A1, EIF4A3, MAGOH, PAXIP1, BARD1, SAP18, VTN, TCOF1, SRSF6, S100A9, PRKDC, NHP2L1, NFIA, SEPT2, MSH2, IK, EPRS, DHX15, BCAS2, TRIM55, THOC6, ZNF687, SMU1, TRMT112, TRA2A, PHGDH, NCSTN,
Protein Size: 262

Molekulargewicht: 29 kDa

Gen-ID: 10772

NCBI Accession: NM_054016, NP_473357

UniProt: O75494

Pathways: Ribonucleoprotein Complex Subunit Organization