HEXIM2 Antikörper (N-Term)

Produktnummer ABIN502066

Produktdetails anti-HEXIM2 Antikörper

Target: HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Schwein, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HEXIM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MATPNQTACN AESPVALEEA KTSGAPGSPQ TPPERHDSGG SLPLTPRMES

Homologie: Dog: 93%, Horse: 79%, Human: 100%, Pig: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HEXIM2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HEXIM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 286 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HEXIM2

Target: HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))

Andere Bezeichnung: HEXIM2 (HEXIM2 Produkte)

Hintergrund: HEXIM2 belongs to the HEXIM family. It is transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor.In cooperation with 7SK snRNA, HEXIM2 sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Alias Symbols: FLJ32384, L3
Protein Interaction Partner: TCF12, CCDC36, HEXIM2, PRDM14, RNPS1, TADA3, SPRY2, SPRY1, PIN1, PIM1, MEOX2, GATA1, CDK9, RN7SK, HEXIM1, TERF2, TERF1, MEPCE, CCNT1,
Protein Size: 286

Molekulargewicht: 31 kDa

Gen-ID: 124790

NCBI Accession: NM_144608, NP_653209

UniProt: Q96MH2