FZD2 Antikörper (N-Term)

Produktnummer ABIN2776701

Produktdetails anti-FZD2 Antikörper

Target: FZD2 (Frizzled Family Receptor 2 (FZD2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MRPRSALPRL LLPLLLLPAA GPAQFHGEKG ISIPDHGFCQ PISIPLCTDI

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FZD2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FZD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 565 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FZD2 Antikörper (ABIN2776701)

Li, Chen, Hu, Xing, Sasaki, Villosis, Li, Nishita, Minami, Minoo: "Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2." in: BMC molecular biology, Vol. 9, pp. 11, (2008) (PubMed).

Details zu FZD2

Target: FZD2 (Frizzled Family Receptor 2 (FZD2))

Andere Bezeichnung: FZD2 (FZD2 Produkte)

Hintergrund: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The expression of the FZD2 gene appears to be developmentally regulated, with high levels of expression in fetal kidney and lung an
Alias Symbols: Fz2, fz-2, fzE2, hFz2
Protein Interaction Partner: UBC, WNT3A, WNT5A, DLG4, ROR2,
Protein Size: 565

Molekulargewicht: 63 kDa

Gen-ID: 2535

NCBI Accession: NM_001466, NP_001457

UniProt: Q14332

Pathways: WNT Signalweg