HSD11B2 Antikörper (N-Term)

Produktnummer ABIN2776772

Produktdetails anti-HSD11B2 Antikörper

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Pferd, Meerschweinchen, Kaninchen, Schaf, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD11B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ERWPWPSGGA WLLVAARALL QLLRSDLRLG RPLLAALALL AALDWLCQRL

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HSD11B2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HSD11B2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 44 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HSD11B2

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Andere Bezeichnung: HSD11B2 (HSD11B2 Produkte)

Synonyme: MGC81883 antikoerper, 11-HSD2 antikoerper, AME antikoerper, AME1 antikoerper, HSD11K antikoerper, HSD2 antikoerper, SDR9C3 antikoerper, 11HSD2 antikoerper, HSD11B2 antikoerper, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog antikoerper, hydroxysteroid 11-beta dehydrogenase 2 antikoerper, hsd11b2.L antikoerper, HSD11B2 antikoerper, Hsd11b2 antikoerper

Hintergrund: HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Alias Symbols: AME, AME1, HSD11K, HSD2, SDR9C3
Protein Interaction Partner: KAT2B, HDAC1, KAT2A, CTBP1,
Protein Size: 44

Molekulargewicht: 45 kDa

Gen-ID: 3291

NCBI Accession: NM_000196, NP_000187

UniProt: P80365

Pathways: Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones