DPYS Antikörper (Middle Region)

Produktnummer ABIN2776833

Produktdetails anti-DPYS Antikörper

Target: DPYS (Dihydropyrimidinase (DPYS))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPYS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRPDPSTPDF LMNLLANDDL TTTGTDNCTF NTCQKALGKD DFTKIPNGVN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DPYS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DPYS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 519 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DPYS Antikörper (ABIN2776833)

Thomas, Chen, Lin, Tomlinson, Lam, Liu, Yeung, Chan, Wong: "Middle cerebral artery stenosis increased the risk of vascular disease mortality among type 2 diabetic patients." in: Cerebrovascular diseases (Basel, Switzerland), Vol. 25, Issue 3, pp. 261-7, (2008) (PubMed).

Details zu DPYS

Target: DPYS (Dihydropyrimidinase (DPYS))

Andere Bezeichnung: DPYS (DPYS Produkte)

Hintergrund: Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
Alias Symbols: DHP, DHPase
Protein Interaction Partner: DPYSL5,
Protein Size: 519

Molekulargewicht: 56 kDa

Gen-ID: 1807

NCBI Accession: NM_001385, NP_001376

UniProt: Q14117