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Desmin Antikörper (Middle Region)

Name: Desmin Antikörper (Middle Region)
SKU: ABIN2776843
Price: 534.11 EUR
Availability: InStock

DES Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated

WB Suggested Anti-DES Antibody Titration: 0. (Desmin Antikörper (Middle Region))

Host: Mouse Target Name: DES Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml (Desmin Antikörper (Middle Region))

Host: Rabbit Target Name: DES Sample Type: Human Fetal Lung Antibody Dilution: 1. (Desmin Antikörper (Middle Region))

Host: Rabbit Target Name: DES Sample Type: Human Fetal Heart Antibody Dilution: 1. (Desmin Antikörper (Middle Region))

4 Abbildungen

Produktnummer ABIN2776843

Datenblatt (PDF)

Target Alle Desmin (DES) Antikörper anzeigen

Desmin (DES)
Bindungsspezifität
16

16

16

15

12

10

7

5

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Middle Region
Reaktivität
157

85

83

36

18

13

12

8

7

4

4

3

2

1
Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen
Wirt
115

42

2
Kaninchen
Passende Sekundärantikörper
Klonalität
108

51

1
Polyklonal
Konjugat
83

8

7

6

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Desmin Antikörper ist unkonjugiert
Applikation
117

70

51

45

29

23

14

13

11

8

8

3

2

2

2

2

1

1
Western Blotting (WB)

Sequenz

MALDVEIATY RKLLEGEESR INLPIQTYSA LNFRETSPEQ RGSEVHTKKT

Homologie

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale

This is a rabbit polyclonal antibody against DES. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung

Affinity Purified

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human DES

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DES Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Maus Monoclonal 3E1G4 unconjugated

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DES Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 10H7D2 unconjugated

Applikationshinweise

Optimal working dilutions should be determined experimentally by the investigator.

Kommentare

Antigen size: 470 AA

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

Desmin (DES)

Andere Bezeichnung

DES (DES Produkte)

Hintergrund

DES is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in its gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793
Protein Interaction Partner: PPP1R18, UBE2I, EHHADH, TRIM63, TRIM55, UBC, YWHAQ, MAPKAPK2, CAPN1, MLH1, AURKB, HADHB, MYL6, JUP, HSP90AA5P, HNRNPUL1, CCT7, SNRNP70, RPL29, RPL17, UBD, CRYAB, SHBG, SP1, ITSN1, NEB, PLEKHA5, SYNC, TRIM7, SYNM, ROCK1, PKD1, SPTAN1, S100B, S100A1, DSP,
Protein Size: 470

Molekulargewicht

53 kDa

Gen-ID

1674

NCBI Accession

NM_001927, NP_001918

UniProt

P17661