MARCO Antikörper (C-Term)

Produktnummer ABIN2776891

Produktdetails anti-MARCO Antikörper

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GPAGVKGEQG SPGLAGPKGA PGQAGQKGDQ GVKGSSGEQG VKGEKGERGE

Homologie: Horse: 86%, Human: 100%, Mouse: 85%, Rat: 85%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against MARCO. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MARCO

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 520 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MARCO

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Andere Bezeichnung: MARCO (MARCO Produkte)

Synonyme: AI323439 antikoerper, Ly112 antikoerper, Scara2 antikoerper, SCARA2 antikoerper, macrophage receptor with collagenous structure antikoerper, MARCO antikoerper, Marco antikoerper

Hintergrund: The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
Alias Symbols: SCARA2
Protein Interaction Partner: SCGB3A2, SCGB3A1,
Protein Size: 520

Molekulargewicht: 53 kDa

Gen-ID: 8685

NCBI Accession: NM_006770, NP_006761

UniProt: Q9UEW3

Pathways: Activation of Innate immune Response