RAGE Antikörper (C-Term)
-
- Target Alle RAGE (AGER) Antikörper anzeigen
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser RAGE Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- RIRAGNSSPG PGDPGRPGDS RPAHWGHLVA KAATPRRGEE GPRKPGGRGG
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against AGER. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human AGER
- Top Product
- Discover our top product AGER Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 342 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- Andere Bezeichnung
- AGER (AGER Produkte)
- Synonyme
- RAGE antikoerper, AGER antikoerper, advanced glycosylation end-product specific receptor antikoerper, advanced glycosylation end product-specific receptor antikoerper, MAPK/MAK/MRK overlapping kinase antikoerper, AGER antikoerper, Ager antikoerper, LOC719012 antikoerper
- Hintergrund
-
AGER mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. It is receptor for amyloid beta peptide.This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: MGC22357, RAGE
Protein Size: 342 - Molekulargewicht
- 38 kDa
- Gen-ID
- 177
- NCBI Accession
- NM_172197, NP_751947
- UniProt
- A2BFI7
- Pathways
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteine
-