ALAD Antikörper (Middle Region)

Produktnummer ABIN2776922

Produktdetails anti-ALAD Antikörper

Target: ALAD (Aminolevulinate Dehydratase (ALAD))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALAD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SVMSYSAKFA SCFYGPFRDA AKSSPAFGDR RCYQLPPGAR GLALRAVDRD

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Yeast: 86%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ALAD. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALAD

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 359 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ALAD

Target: ALAD (Aminolevulinate Dehydratase (ALAD))

Andere Bezeichnung: ALAD (ALAD Produkte)

Synonyme: DDBDRAFT_0190269 antikoerper, DDBDRAFT_0231415 antikoerper, DDB_0190269 antikoerper, DDB_0231415 antikoerper, ALAD antikoerper, ncf antikoerper, ALADH antikoerper, PBGS antikoerper, ALADR antikoerper, aminolevulinatedelta-dehydratase antikoerper, zgc:110219 antikoerper, Lv antikoerper, delta-aminolevulinate dehydratase antikoerper, aminolevulinate dehydratase antikoerper, delta-aminolevulinic acid dehydratase antikoerper, Delta-aminolevulinic acid dehydratase antikoerper, aminolevulinate dehydratase L homeolog antikoerper, aminolevulinate, delta-, dehydratase antikoerper, hemB antikoerper, ALAD antikoerper, PBGS antikoerper, STY0404 antikoerper, SAS1597 antikoerper, SACI_RS03725 antikoerper, PAAG_00299 antikoerper, VDBG_00315 antikoerper, HPPC_00830 antikoerper, MGYG_01952 antikoerper, hem2 antikoerper, alad.L antikoerper, Alad antikoerper, alad antikoerper

Hintergrund: The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: ALADH, MGC5057, PBGS
Protein Interaction Partner: C14orf142, P3H1, RPRD1B, PPME1, LAP3, DBNL, HSPBP1, GPN1, WDR4, ACTR2, TOM1L1, ZPR1, OGT, SURF2, LPP, AGFG1, UBD, UBC, ALAD,
Protein Size: 359

Molekulargewicht: 39 kDa

Gen-ID: 210

NCBI Accession: NM_001003945, NP_001003945

UniProt: Q6ZMU0