ALAS2 Antikörper (C-Term)

Produktnummer ABIN2776924

Produktdetails anti-ALAS2 Antikörper

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Schaf, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALAS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PTVPRGEELL RLAPSPHHSP QMMEDFVEKL LLAWTAVGLP LQDVSVAACN

Homologie: Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 79%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against ALAS2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ALAS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 550 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ALAS2 Antikörper (ABIN2776924)

Chien, Chang, Lee, Su, Wu: "Non-genomic immunosuppressive actions of progesterone inhibits PHA-induced alkalinization and activation in T cells." in: Journal of cellular biochemistry, Vol. 99, Issue 1, pp. 292-304, (2006) (PubMed).

Details zu ALAS2

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Andere Bezeichnung: ALAS2 (ALAS2 Produkte)

Synonyme: anh1 antikoerper, asb antikoerper, xlsa antikoerper, ALAS-E antikoerper, ALASE antikoerper, ANH1 antikoerper, ASB antikoerper, XLDPP antikoerper, XLEPP antikoerper, XLSA antikoerper, alas-e antikoerper, cb1063 antikoerper, sau antikoerper, sauternes antikoerper, ALAS antikoerper, Alas-2 antikoerper, 5'-aminolevulinate synthase 2 antikoerper, aminolevulinate, delta-, synthase 2 antikoerper, aminolevulinic acid synthase 2, erythroid antikoerper, alas2 antikoerper, ALAS2 antikoerper, Alas2 antikoerper, alas2.L antikoerper

Hintergrund: ALAS2 specifies an erythroid-specific mitochondrially located enzyme. The protein catalyzes the first step in the heme biosynthetic pathway. Defects in its gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: ANH1, ASB, XLSA, ALASE, XLDPP, XLEPP, ALAS-E
Protein Interaction Partner: BANP, GRB2, SUCLA2, RABGGTB,
Protein Size: 550

Molekulargewicht: 60 kDa

Gen-ID: 212

NCBI Accession: NM_001037967, NP_001033056

UniProt: P22557

Pathways: Transition Metal Ion Homeostasis