HSD17B1 Antikörper (N-Term)

Produktnummer ABIN2776958

Produktdetails anti-HSD17B1 Antikörper

Target: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MARTVVLITG CSSGIGLHLA VRLASDPSQS FKVYATLRDL KTQGRLWEAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HSD17B1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HSD17B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 328 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HSD17B1 Antikörper (ABIN2776958)

Tsuchiya, Nakao, Katoh, Sasaki, Hiroshima, Tanaka, Matsunaga, Hanaoka, Tsugane, Ikenoue: "Association between endometriosis and genetic polymorphisms of the estradiol-synthesizing enzyme genes HSD17B1 and CYP19." in: Human reproduction (Oxford, England), Vol. 20, Issue 4, pp. 974-8, (2005) (PubMed).

Details zu HSD17B1

Target: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Andere Bezeichnung: HSD17B1 (HSD17B1 Produkte)

Synonyme: EDH17B2 antikoerper, EDHB17 antikoerper, HSD17 antikoerper, SDR28C1 antikoerper, 17HSDB1 antikoerper, 17beta-HSD antikoerper, E2DH antikoerper, Hsd17ba antikoerper, 17BHD1 antikoerper, zfHSD17B1 antikoerper, hydroxysteroid 17-beta dehydrogenase 1 antikoerper, hydroxysteroid (17-beta) dehydrogenase 1 antikoerper, HSD17B1 antikoerper, Hsd17b1 antikoerper, hsd17b1 antikoerper

Hintergrund: HSD17B1 is favors the reduction of estrogens and androgens. It also has 20-alpha-HSD activity. It uses preferentially NADH.
Alias Symbols: EDH17B2, EDHB17, HSD17, SDR28C1
Protein Interaction Partner: HSD17B1,
Protein Size: 328

Molekulargewicht: 36 kDa

Gen-ID: 3292

NCBI Accession: NM_000413, NP_000404

UniProt: P14061

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis