GSTM1 Antikörper (C-Term)

Produktnummer ABIN2776985

Produktdetails anti-GSTM1 Antikörper

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PEKLKLYSEF LGKRPWFAGN KGLEKISAYM KSSRFLPRPV FSKMAVWGNK

Homologie: Cow: 86%, Dog: 79%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GSTM1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GSTM1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 181 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GSTM1

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Andere Bezeichnung: GSTM1 (GSTM1 Produkte)

Synonyme: GST1 antikoerper, GSTM1-1 antikoerper, GSTM1a-1a antikoerper, GSTM1b-1b antikoerper, GTH4 antikoerper, GTM1 antikoerper, H-B antikoerper, MU antikoerper, MU-1 antikoerper, GSTA3 antikoerper, Gstb-1 antikoerper, Gstb1 antikoerper, gst-mu antikoerper, gst1 antikoerper, gstm1 antikoerper, gstm2 antikoerper, gth4 antikoerper, gtm1 antikoerper, glutathione S-transferase mu 1 antikoerper, glutathione S-transferase M1 antikoerper, glutathione S-transferase, mu 1 antikoerper, glutathione S-transferase Mu 1 antikoerper, glutathione S-transferase mu 2 (muscle) antikoerper, glutathione S-transferase mu 1 L homeolog antikoerper, GSTM1 antikoerper, Gstm1 antikoerper, LOC100356307 antikoerper, GSTM2 antikoerper, LOC100731426 antikoerper, gstm1.L antikoerper

Hintergrund: Cytosolic and membrane-bound forms of glutathione S-transferase are two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM1 a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.
Alias Symbols: GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MGC26563, MU, MU-1
Protein Interaction Partner: GSTM3, UBC, IQCB1, MAP3K5, GSTM2, GSTM1,
Protein Size: 181

Molekulargewicht: 21 kDa

Gen-ID: 2944

NCBI Accession: NM_146421, NP_666533

UniProt: P09488

Pathways: Negative Regulation of Transporter Activity