CYP2C19 Antikörper (Middle Region)
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- Target Alle CYP2C19 Antikörper anzeigen
- CYP2C19 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Ziege, Meerschweinchen, Pferd, Schwein, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYP2C19 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- QEEIERVIGR NRSPCMQDRG HMPYTDAVVH EVQRYIDLIP TSLPHAVTCD
- Homologie
- Cow: 86%, Dog: 86%, Goat: 75%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 92%, Rabbit: 93%, Rat: 92%, Sheep: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CYP2C19. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CYP2C19
- Top Product
- Discover our top product CYP2C19 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 490 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms." in: Cancer research, Vol. 68, Issue 14, pp. 5997-6005, (2008) (PubMed).
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Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms." in: Cancer research, Vol. 68, Issue 14, pp. 5997-6005, (2008) (PubMed).
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- Target
- CYP2C19 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19))
- Andere Bezeichnung
- CYP2C19 (CYP2C19 Produkte)
- Synonyme
- CPCJ antikoerper, CYP2C antikoerper, P450C2C antikoerper, P450IIC19 antikoerper, cytochrome P450 family 2 subfamily C member 19 antikoerper, cytochrome P450, family 2, subfamily C, polypeptide 19 antikoerper, cytochrome P450 2C19 antikoerper, CYP2C19 antikoerper
- Hintergrund
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CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CPCJ, CYP 2C, CYP2C, P450C2C, P450IIC19
Protein Interaction Partner: POR,
Protein Size: 490 - Molekulargewicht
- 56 kDa
- Gen-ID
- 1557
- NCBI Accession
- NM_000769, NP_000760
- UniProt
- P33261
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