HSD3B1 Antikörper (N-Term)
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- Target Alle HSD3B1 Antikörper anzeigen
- HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Ratte, Schwein, Schaf, Rind (Kuh), Ziege, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HSD3B1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- TGWSCLVTGA GGFLGQRIIR LLVKEKELKE IRVLDKAFGP ELREEFSKLQ
- Homologie
- Cow: 79%, Goat: 82%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 79%, Sheep: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against HSD3B1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HSD3B1
- Top Product
- Discover our top product HSD3B1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 373 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer." in: Oncotarget, Vol. 7, Issue 38, pp. 62240-62254, (2016) (PubMed).
: "
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Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer." in: Oncotarget, Vol. 7, Issue 38, pp. 62240-62254, (2016) (PubMed).
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- Target
- HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))
- Andere Bezeichnung
- HSD3B1 (HSD3B1 Produkte)
- Hintergrund
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3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
Alias Symbols: HSD3B, HSDB3, I, HSDB3A, SDR11E1, 3BETAHSD
Protein Size: 373 - Molekulargewicht
- 42 kDa
- Gen-ID
- 3283
- NCBI Accession
- NM_000862, NP_000853
- UniProt
- P14060
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis
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