DHODH Antikörper (C-Term)

Produktnummer ABIN2777080

Produktdetails anti-DHODH Antikörper

Target: DHODH (Dihydroorotate Dehydrogenase (DHODH))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHODH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GGLSGKPLRD LSTQTIREMY ALTQGRVPII GVGGVSSGQD ALEKIRAGAS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against DHODH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DHODH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 395 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DHODH Antikörper (ABIN2777080)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu DHODH

Target: DHODH (Dihydroorotate Dehydrogenase (DHODH))

Andere Bezeichnung: DHODH (DHODH Produkte)

Synonyme: DHOdehase antikoerper, POADS antikoerper, URA1 antikoerper, 2810417D19Rik antikoerper, AI834883 antikoerper, DDBDRAFT_0167009 antikoerper, DDBDRAFT_0185217 antikoerper, DDB_0167009 antikoerper, DDB_0185217 antikoerper, DHOD antikoerper, DHODase antikoerper, XFHB_12025 antikoerper, dhodh antikoerper, dihydroorotate dehydrogenase (quinone) antikoerper, dihydroorotate dehydrogenase antikoerper, dihydroorotate dehydrogenase (quinone) L homeolog antikoerper, DHODH antikoerper, Dhodh antikoerper, pyrD antikoerper, pyr4 antikoerper, Mrub_0263 antikoerper, Arnit_2124 antikoerper, Trad_2703 antikoerper, Ftrac_1484 antikoerper, Ndas_0799 antikoerper, Mesil_1876 antikoerper, Slip_0841 antikoerper, Spirs_1436 antikoerper, XFHB_RS12780 antikoerper, dhodh.L antikoerper

Hintergrund: DHODH catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DHOdehase, URA1, POADS
Protein Interaction Partner: UBC, TMED10, MT2A, FKBP8, SSBP1, SDHA, PLP2, OGDH, NDUFS8, HNRNPM, ILF3, CYC1,
Protein Size: 395

Molekulargewicht: 43 kDa

Gen-ID: 1723

NCBI Accession: NM_001361, NP_001352

UniProt: Q02127

Pathways: Ribonucleoside Biosynthetic Process, Protein targeting to Nucleus