TNNI1 Antikörper (N-Term)

Produktnummer ABIN2777151

Produktdetails anti-TNNI1 Antikörper

Target: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Ziege, Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNNI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MPEVERKPKI TASRKLLLKS LMLAKAKECW EQEHEEREAE KVRYLAERIP

Homologie: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNNI1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TNNI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 187 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TNNI1 Antikörper (ABIN2777151)

Salzler, Shah, Doré, Bauerlein, Miloscio, Latres, Papadopoulos, Olson, MacDonald, Duan: "Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle." in: Proteomics, Vol. 16, Issue 14, pp. 2019-27, (2016) (PubMed).

Details zu TNNI1

Target: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Andere Bezeichnung: TNNI1 (TNNI1 Produkte)

Synonyme: ANM antikoerper, NEM5 antikoerper, STNT antikoerper, TNT antikoerper, TNTS antikoerper, TnI-S4 antikoerper, SSTNI antikoerper, TNN1 antikoerper, 2700018B22Rik antikoerper, AI747285 antikoerper, ssTnI antikoerper, AW146156 antikoerper, Tnt antikoerper, sTnT antikoerper, ssTnT antikoerper, Fang2 antikoerper, tnTs antikoerper, troponin 1 antikoerper, zgc:86895 antikoerper, troponin T1, slow skeletal type antikoerper, troponin I1, slow skeletal type antikoerper, troponin I, skeletal, slow 1 antikoerper, troponin T1, skeletal, slow antikoerper, troponin I1, slow skeletal type S homeolog antikoerper, troponin I type 1 (skeletal, slow) antikoerper, troponin I4b, tandem duplicate 2 antikoerper, TNNT1 antikoerper, TNNI1 antikoerper, Tnni1 antikoerper, Tnnt1 antikoerper, tnni1.S antikoerper, tnni4b.2 antikoerper

Hintergrund: Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 Molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.
Alias Symbols: DKFZp451O223, TNN1, SSTNI
Protein Interaction Partner: PNMA1, MDFI, TRIM63, TRIM55, TNNC1, TNNT2, EIF3I, CCDC85B, TNNT1, ACTA1, PKD2L1,
Protein Size: 187

Molekulargewicht: 21 kDa

Gen-ID: 7135

NCBI Accession: NM_003281, NP_003272

UniProt: P19237