UPP1 Antikörper (N-Term)

Produktnummer ABIN2777156

Produktdetails anti-UPP1 Antikörper

Target: UPP1 (Uridine Phosphorylase 1 (UPP1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Pferd, Ratte, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UPP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AATGANAEKA ESHNDCPVRL LNPNIAKMKE DILYHFNLTT SRHNFPALFG

Homologie: Cow: 85%, Guinea Pig: 75%, Horse: 83%, Human: 100%, Mouse: 85%, Rat: 85%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against UPP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UPP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 310 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-UPP1 Antikörper (ABIN2777156)

Temmink, de Bruin, Laan, Turksma, Cricca, Masterson, Noordhuis, Peters: "The role of thymidine phosphorylase and uridine phosphorylase in (fluoro)pyrimidine metabolism in peripheral blood mononuclear cells." in: The international journal of biochemistry & cell biology, Vol. 38, Issue 10, pp. 1759-65, (2006) (PubMed).

Details zu UPP1

Target: UPP1 (Uridine Phosphorylase 1 (UPP1))

Andere Bezeichnung: UPP1 (UPP1 Produkte)

Hintergrund: UPP1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Alias Symbols: UDRPASE, UP, UPASE, UPP
Protein Interaction Partner: CTDP1, YRDC, WDR45B, WBP2, UCK2, UBE2D1, MPST, UBC, EBNA-LP, VIM,
Protein Size: 310

Molekulargewicht: 34 kDa

Gen-ID: 7378

NCBI Accession: NM_003364, NP_003355

UniProt: Q16831

Pathways: Ribonucleoside Biosynthetic Process