TH Antikörper (N-Term)
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- Target Alle TH Produkte
- TH
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Maus, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TH Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GAPGPSLTGS PWPGTAAPAA SYTPTPRSPR FIGRRQSLIE DARKEREAAV
- Homologie
- Cow: 91%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TH. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the n terminal region of human TH
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 528 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TH
- Abstract
- TH Produkte
- Hintergrund
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The specific function of the protein remains unknown. The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: TYH, DYT14, DYT5b
Protein Interaction Partner: TYSND1, YWHAQ, MAPKAPK2, CDK11B, RPS6KA5, CAMK2G, MAPK3, PRKACA, YWHAB, YWHAZ, MAPK1, SNCA, CSNK2A1,
Protein Size: 528 - Molekulargewicht
- 58 kDa
- Gen-ID
- 7054
- NCBI Accession
- NM_199292, NP_954986
- UniProt
- P07101
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