CBFB Antikörper (N-Term)
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- Target Alle CBFB Antikörper anzeigen
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio), Pferd, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen, Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CBFB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CBFB. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CBFB
- Top Product
- Discover our top product CBFB Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 182 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
- Andere Bezeichnung
- CBFB (CBFB Produkte)
- Synonyme
- PEBP2B antikoerper, Cbfb antikoerper, pebp2b antikoerper, Pebp2 antikoerper, CBFB antikoerper, unp1266 antikoerper, cbf-beta antikoerper, cbfbeta antikoerper, pea2-beta antikoerper, pebp2-beta antikoerper, AI893578 antikoerper, PEA2 antikoerper, PEBP2b antikoerper, Pebpb2 antikoerper, core-binding factor beta subunit antikoerper, core binding factor beta subunit antikoerper, core-binding factor, beta subunit antikoerper, core-binding factor, beta subunit S homeolog antikoerper, core binding factor beta antikoerper, CBFB antikoerper, Cbfb antikoerper, cbfb antikoerper, cbfb.S antikoerper
- Hintergrund
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CBFB encodes a protein that is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.
Alias Symbols: PEBP2B
Protein Interaction Partner: vif, CUL5, UBC, RAB2A, MYC, nef, APOBEC3G, RUNX1, ELAVL1, KMT2A, COPRS, RUNX3, MYOD1, CHGB, CBFA2T2, RUNX2, CBFB, C1QBP,
Protein Size: 182 - Molekulargewicht
- 21 kDa
- Gen-ID
- 865
- NCBI Accession
- NM_001755, NP_001746
- UniProt
- Q13951
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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