NFYB Antikörper (Middle Region)
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- Target Alle NFYB Antikörper anzeigen
- NFYB (Nuclear Transcription Factor Y, beta (NFYB))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Meerschweinchen, Kaninchen, Pferd, Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NFYB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- EAMKGEKGIG GAVTATDGLS EELTEEAFTN QLPAGLITTD GQQQNVMVYT
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%
- Produktmerkmale
- This is a rabbit polyclonal antibody against NFYB. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human NFYB
- Top Product
- Discover our top product NFYB Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 207 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NFYB (Nuclear Transcription Factor Y, beta (NFYB))
- Andere Bezeichnung
- NFYB (NFYB Produkte)
- Synonyme
- CBF-A antikoerper, CBF-B antikoerper, HAP3 antikoerper, NF-YB antikoerper, NFYB antikoerper, nfyb antikoerper, zgc:110533 antikoerper, zgc:110552 antikoerper, hap3 antikoerper, cbf-a antikoerper, cbf-b antikoerper, CBFB antikoerper, Nfya antikoerper, AA985999 antikoerper, Cbf-A antikoerper, nuclear transcription factor Y subunit beta antikoerper, nuclear transcription factor Y subunit beta L homeolog antikoerper, nuclear transcription factor Y, beta b antikoerper, nuclear transcription factor Y, beta a antikoerper, nuclear transcription factor-Y beta antikoerper, NFYB antikoerper, nfyb.L antikoerper, nfybb antikoerper, nfyba antikoerper, nfyb antikoerper, Nfyb antikoerper
- Hintergrund
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NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants.
Alias Symbols: CBF-A, CBF-B, HAP3, NF-YB
Protein Interaction Partner: AGTRAP, POLE4, DRAP1, NFYA, LYN, CDK2, CCNE1, CCNA2, TP53, SMYD3, NFYC, MAOB, UBC, CREBBP, SP1, HDAC1, EP300, KAT2B, TP73, TAF12, TAF11, TAF6, GRB2, YBX3, CEBPZ, C1QBP, TBP, CIITA, CNTN2, MYC, ELF1, YBX1,
Protein Size: 207 - Molekulargewicht
- 23 kDa
- Gen-ID
- 4801
- NCBI Accession
- NM_006166, NP_006157
- UniProt
- P25208
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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