NFYA Antikörper (C-Term)

Produktnummer ABIN2777243

Der Kaninchen Polyklonal Anti-NFYA-Antikörper wurde für WB und IHC validiert. Er ist geeignet, NFYA in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Saccharomyces cerevisiae zu detektieren.

Kurzübersicht für NFYA Antikörper (C-Term) (ABIN2777243)

Target: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFYA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NFYA Antikörper

Bindungsspezifität: C-Term

Sequenz: YLHESRHRHA MARKRGEGGR FFSPKEKDSP HMQDPNQADE EAMTQIIRVS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against NFYA. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NFYA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 347 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NFYA

Target: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Andere Bezeichnung: NFYA

Hintergrund: NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
Alias Symbols: HAP2, CBF-A, CBF-B, NF-YA
Protein Interaction Partner: LUC7L2, POGZ, NFYB, GTF2A1, CSNK2A1, UBC, APPBP2, TP63, TP53, NFYC, EP300, CDK2, CCNA2, CDC25A, APP, RPS6KA6, JUN, HDAC1, ATF2, SP1, TAF6, TAF11, TAF12, PAPOLG, PWP1, SREBF2, ZHX2, ZHX1, ZHX3, KPNB1, SRSF1, HMGA1, SRF, USF2, USF1, NFYA, NR5A1, POU2F1, CEB
Protein Size: 347

Molekulargewicht: 37 kDa

Gen-ID: 4800

NCBI Accession: NM_002505, NP_002496

UniProt: P23511

Pathways: Regulation of Lipid Metabolism by PPARalpha