Msx2/Hox8 Antikörper (N-Term)

Produktnummer ABIN2777276

Produktdetails anti-Msx2/Hox8 Antikörper

Target: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Msx2/Hox8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MASPSKGNDL FSPDEEGPAV VAGPGPGPGG AEGAAEERRV KVSSLPFSVE

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 91%, Rabbit: 91%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against MSX2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human MSX2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 267 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Msx2/Hox8

Target: Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))

Andere Bezeichnung: MSX2 (Msx2 Produkte)

Synonyme: CRS2 antikoerper, FPP antikoerper, HOX8 antikoerper, MSH antikoerper, PFM antikoerper, PFM1 antikoerper, BB122635 antikoerper, Hox-8 antikoerper, Hox8 antikoerper, Hox8.1 antikoerper, HOX-8 antikoerper, Msx-2 antikoerper, msh homeobox 2 antikoerper, MSX2 antikoerper, Msx2 antikoerper

Hintergrund: MSX2 probable play a morphogenetic role. MSX2 may play a role in limb-pattern formation. In osteoblasts, MSX2 suppresses transcription driven by the osteocalcin FGF response element (OCFRE).This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CRS2, FPP, HOX8, MSH, PFM, PFM1
Protein Interaction Partner: ATXN1, PIAS2, UBC, XRCC5, XRCC6, ZDHHC2, TLE2, TLE1, PPARG, POU2AF1, NR3C1, POLR3D, SPEN, ZBTB17, RUNX2, DLX5, MAGED1, GTF2F2, GTF2F1, MSX1, DLX2, MSX2, CEBPA, PITX2,
Protein Size: 267

Molekulargewicht: 29 kDa

Gen-ID: 4488

NCBI Accession: NM_002449, NP_002440

UniProt: P35548