HOXA5 Antikörper (Middle Region)

Produktnummer ABIN2777305

Produktdetails anti-HOXA5 Antikörper

Target: HOXA5 (Homeobox A5 (HOXA5))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: VGTASGAEED APASSEQASA QSEPSPAPPA QPQIYPWMRK LHISHDNIGG

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXA5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXA5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 270 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HOXA5 Antikörper (ABIN2777305)

Heshmati, Kharazi, Türköz, Chang, Kamali Dolatabadi, Boström, Krstic, Boukoura, Wagner, Kadri, Månsson, Altun, Qian, Walfridsson: "The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation." in: Scientific reports, Vol. 8, Issue 1, pp. 11202, (2019) (PubMed).

Boucherat, Montaron, Bérubé-Simard, Aubin, Philippidou, Wellik, Dasen, Jeannotte: "Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 304, Issue 12, pp. L817-30, (2013) (PubMed).

Details zu HOXA5

Target: HOXA5 (Homeobox A5 (HOXA5))

Andere Bezeichnung: HOXA5 (HOXA5 Produkte)

Synonyme: HOX1 antikoerper, HOX1.3 antikoerper, HOX1C antikoerper, Hox-1.3 antikoerper, HOXA5 antikoerper, hox1 antikoerper, hox1c antikoerper, hox1.3 antikoerper, Hoxa-5 antikoerper, homeobox A5 antikoerper, homeobox protein Hox-A5 antikoerper, homeo box A5 antikoerper, hoxa5a protein antikoerper, HOXA5 antikoerper, Hoxa5 antikoerper, LOC463310 antikoerper, hoxa5 antikoerper, hoxa5a antikoerper

Hintergrund: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.
Alias Symbols: HOX1, HOX1.3, HOX1C, MGC9376
Protein Interaction Partner: PRMT6, TWIST1, UBC, ELAVL1, SOX2, ZNF408, GTF2A1L, SMAD1, DDIT3, PBX1, MEIS1, FOXA2, CDX4, FOXO1,
Protein Size: 270

Molekulargewicht: 29 kDa

Gen-ID: 3202

NCBI Accession: NM_019102, NP_061975

UniProt: Q6FG31