FOXP4 Antikörper (Middle Region)

Produktnummer ABIN2777345

Produktdetails anti-FOXP4 Antikörper

Target: FOXP4 (Forkhead Box P4 (FOXP4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PRLSPPQYSH QVQVKEEPAE AEEDRQPGPP LGAPNPSASG PPEDRDLEEE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXP4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXP4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 680 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FOXP4 Antikörper (ABIN2777345)

Tuovinen, Kekäläinen, Rossi, Puntila, Arstila: "Cutting edge: human CD4-CD8- thymocytes express FOXP3 in the absence of a TCR." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 6, pp. 3651-4, (2008) (PubMed).

Details zu FOXP4

Target: FOXP4 (Forkhead Box P4 (FOXP4))

Andere Bezeichnung: FOXP4 (FOXP4 Produkte)

Hintergrund: FOXP4 belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. FOXP4 may play a role in the development of tumors of the kidney and larynx. This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
Alias Symbols: FLJ40908, FLJ44184, hFKHLA
Protein Interaction Partner: SOX2, MKI67, SUMO2, UBC, FOXP1, FOXP4, FOXP2,
Protein Size: 680

Molekulargewicht: 73 kDa

Gen-ID: 116113

NCBI Accession: NM_138457, NP_612466

UniProt: Q8IW55