AEBP1 Antikörper (N-Term)

Produktnummer ABIN2777370

Produktdetails anti-AEBP1 Antikörper

Target: AEBP1 (AE Binding Protein 1 (AEBP1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AEBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: VPPEKTKDKG KKGKKDKGPK VPKESLEGSP RPPKKGKEKP PKATKKPKEK

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against AEBP1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AEBP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1158 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-AEBP1 Antikörper (ABIN2777370)

Kim, Gieske, Trudgen, Hudgins-Spivey, Kim, Krust, Chambon, Jeong, Blalock, Ko: "Identification of estradiol/ER?-regulated genes in the mouse pituitary." in: The Journal of endocrinology, Vol. 210, Issue 3, pp. 309-21, (2011) (PubMed).

Details zu AEBP1

Target: AEBP1 (AE Binding Protein 1 (AEBP1))

Andere Bezeichnung: AEBP1 (AEBP1 Produkte)

Synonyme: ACLP antikoerper, AE binding protein 1 antikoerper, Closa_4071 antikoerper, AEBP1 antikoerper, Aebp1 antikoerper

Hintergrund: The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.
Alias Symbols: ACLP
Protein Interaction Partner: GRB2, TCF3,
Protein Size: 1158

Molekulargewicht: 131 kDa

Gen-ID: 165

NCBI Accession: NM_001129, NP_001120

UniProt: Q14113