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FGD1 Antikörper (C-Term)

FGD1 Reaktivität: Human, Rind (Kuh), Hund, Schwein, Ratte, Maus, Kaninchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777407
  • Target Alle FGD1 Antikörper anzeigen
    FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
    Bindungsspezifität
    • 3
    • 3
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Rind (Kuh), Hund, Schwein, Ratte, Maus, Kaninchen, Pferd
    Wirt
    • 9
    Kaninchen
    Klonalität
    • 9
    Polyklonal
    Konjugat
    • 9
    Dieser FGD1 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    WMAVLGRAGR GDTFCPGPTL SEDREMEEAP VAALGATAEP PESPQTRDKT
    Homologie
    Cow: 86%, Dog: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against FGD1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human FGD1
    Top Product
    Discover our top product FGD1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 961 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
    Andere Bezeichnung
    FGD1 (FGD1 Produkte)
    Synonyme
    AAS antikoerper, FGDY antikoerper, MRXS16 antikoerper, ZFYVE3 antikoerper, FYVE, RhoGEF and PH domain containing 1 antikoerper, FGD1 antikoerper, Fgd1 antikoerper, fgd1 antikoerper
    Hintergrund
    FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
    Alias Symbols: AAS, FGDY, MRXS16, ZFYVE3
    Protein Interaction Partner: BTRC, UBC, ELAVL1, ELMO1, CTTN, CDC42, AOC1,
    Protein Size: 961
    Molekulargewicht
    107 kDa
    Gen-ID
    2245
    NCBI Accession
    NM_004463, NP_004454
    UniProt
    P98174
    Pathways
    Neurotrophin Signalübertragung
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