FGD1 Antikörper (C-Term)
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- Target Alle FGD1 Antikörper anzeigen
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Rind (Kuh), Hund, Schwein, Ratte, Maus, Kaninchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FGD1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- WMAVLGRAGR GDTFCPGPTL SEDREMEEAP VAALGATAEP PESPQTRDKT
- Homologie
- Cow: 86%, Dog: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FGD1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human FGD1
- Top Product
- Discover our top product FGD1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 961 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
- Andere Bezeichnung
- FGD1 (FGD1 Produkte)
- Synonyme
- AAS antikoerper, FGDY antikoerper, MRXS16 antikoerper, ZFYVE3 antikoerper, FYVE, RhoGEF and PH domain containing 1 antikoerper, FGD1 antikoerper, Fgd1 antikoerper, fgd1 antikoerper
- Hintergrund
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FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
Alias Symbols: AAS, FGDY, MRXS16, ZFYVE3
Protein Interaction Partner: BTRC, UBC, ELAVL1, ELMO1, CTTN, CDC42, AOC1,
Protein Size: 961 - Molekulargewicht
- 107 kDa
- Gen-ID
- 2245
- NCBI Accession
- NM_004463, NP_004454
- UniProt
- P98174
- Pathways
- Neurotrophin Signalübertragung
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