FOXA2 Antikörper (Middle Region)
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- Target Alle FOXA2 Antikörper anzeigen
- FOXA2 (Forkhead Box A2 (FOXA2))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Hund, Pferd, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FOXA2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ASQAQLGEAA GPASETPAGT ESPHSSASPC QEHKRGGLGE LKGTPAAALS
- Homologie
- Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 77%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FOXA2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FOXA2
- Top Product
- Discover our top product FOXA2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 457 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate." in: Stem cells international, Vol. 2014, pp. 298163, (2014) (PubMed).
: "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, (2013) (PubMed).
: "Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 302, Issue 8, pp. L746-54, (2012) (PubMed).
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SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate." in: Stem cells international, Vol. 2014, pp. 298163, (2014) (PubMed).
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- Target
- FOXA2 (Forkhead Box A2 (FOXA2))
- Andere Bezeichnung
- FOXA2 (FOXA2 Produkte)
- Synonyme
- hnf3b antikoerper, tcf3b antikoerper, hnf3beta antikoerper, hnf3-beta antikoerper, FOXA2 antikoerper, HNF3B antikoerper, TCF3B antikoerper, HNF-3B antikoerper, ax antikoerper, axl antikoerper, fkd1 antikoerper, ik:tdsubc_2g8 antikoerper, tdsubc_2g8 antikoerper, wu:fe05g04 antikoerper, xx:tdsubc_2g8 antikoerper, FoxA2-A antikoerper, FoxA2a antikoerper, xFD-3 antikoerper, xbeta-1 antikoerper, HNF-3b antikoerper, HNF3-beta antikoerper, HNF3beta antikoerper, Hnf-3b antikoerper, Hnf3b antikoerper, Tcf-3b antikoerper, Tcf3b antikoerper, HNF-3BETA antikoerper, forkhead box A2 antikoerper, forkhead box A2 L homeolog antikoerper, foxa2 antikoerper, FOXA2 antikoerper, foxa2.L antikoerper, Foxa2 antikoerper
- Hintergrund
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FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene. This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: HNF3B, MGC19807, TCF3B
Protein Interaction Partner: PPARGC1B, GSC, EN2, OTX2, ONECUT1, NCOA1, TLE1, MIP, HOXA5, LHX1,
Protein Size: 457 - Molekulargewicht
- 48 kDa
- Gen-ID
- 3170
- NCBI Accession
- NM_021784, NP_068556
- UniProt
- Q9Y261
- Pathways
- Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
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