FOXA3 Antikörper (Middle Region)

Produktnummer ABIN2777513

Produktdetails anti-FOXA3 Antikörper

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Hund, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: FENGCYLRRQ KRFKLEEKVK KGGSGAATTT RNGTGSAAST TTPAATVTSP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXA3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 350 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FOXA3 Antikörper (ABIN2777513)

Menga, Infantino, Iacobazzi, Convertini, Palmieri, Iacobazzi: "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, (2013) (PubMed).

Details zu FOXA3

Target: FOXA3 (Forkhead Box A3 (FOXA3))

Andere Bezeichnung: FOXA3 (FOXA3 Produkte)

Synonyme: FOXA3 antikoerper, Zffkh1 antikoerper, fa11c04 antikoerper, fkd2 antikoerper, forkhead-2 antikoerper, wu:fa11c04 antikoerper, wu:fc37a08 antikoerper, zf-FKH1 antikoerper, FKHH3 antikoerper, HNF3G antikoerper, TCF3G antikoerper, HNF3-G antikoerper, Hnf-3g antikoerper, Hnf3g antikoerper, Tcf-3g antikoerper, Tcf3g antikoerper, forkhead box A3 antikoerper, FOXA3 antikoerper, foxa3 antikoerper, Foxa3 antikoerper

Hintergrund: FOXA3 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved.
Alias Symbols: FKHH3, HNF3G, TCF3G
Protein Interaction Partner: PPARA, ALX4, TLE2, TLE1, HMGB1,
Protein Size: 350

Molekulargewicht: 37 kDa

Gen-ID: 3171

NCBI Accession: NM_004497, NP_004488

UniProt: P55318

Pathways: Carbohydrate Homeostasis