PAWR Antikörper (Middle Region)

Produktnummer ABIN2777555

Produktdetails anti-PAWR Antikörper

Target: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAWR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SYLLQEPPRT VSGRYKSTTS VSEEDVSSRY SRTDRSGFPR YNRDANVSGT

Homologie: Dog: 100%, Horse: 85%, Human: 100%, Mouse: 91%, Rabbit: 77%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against PAWR. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PAWR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 340 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PAWR

Target: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Andere Bezeichnung: PAWR (PAWR Produkte)

Synonyme: MGC81382 antikoerper, pawrl antikoerper, zgc:103513 antikoerper, PAWR antikoerper, PAR4 antikoerper, Par-4 antikoerper, Par4 antikoerper, 2310001G03Rik antikoerper, pro-apoptotic WT1 regulator antikoerper, PRKC, apoptosis, WT1, regulator L homeolog antikoerper, PRKC, apoptosis, WT1, regulator antikoerper, PAWR antikoerper, pawr.L antikoerper, pawr antikoerper, Pawr antikoerper

Hintergrund: The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
Alias Symbols: PAR4, Par-4
Protein Interaction Partner: FBXO45, UBC, EED, FAM129B, SNX6, CAND1, VPS29, JMJD6, STAT1, SNX2, SHMT2, SHMT1, PPM1G, IDE, H3F3A, CARS, ATP6V1C1, APEH, PAN2, DRD2, DAPK3, SQSTM1, PRKCZ, Spsb4, Spsb2, SPSB1, FBXO25, HSPA5, Cep350, Kif23, THAP1, SLC5A7, AATF, TFPT, PAWR, WT1, RRAS2, ATP
Protein Size: 340

Molekulargewicht: 37 kDa

Gen-ID: 5074

NCBI Accession: NM_002583, NP_002574

UniProt: O75796