PAX7 Antikörper (C-Term)

Produktnummer ABIN2777560

Produktdetails anti-PAX7 Antikörper

Target: PAX7 (Paired Box 7 (PAX7))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: QADFSISPLH GGLDSATSIS ASCSQRADSI KPGDSLPTSQ AYCPPTYSTT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PAX7. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of PAX7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 520 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PAX7 Antikörper (ABIN2777560)

Gautam, Nirwane, Yao: "Laminin differentially regulates the stemness of type I and type II pericytes." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 28, (2017) (PubMed).

Czerwinska, Nowacka, Aszer, Gawrzak, Archacka, Fogtman, Iwanicka-Nowicka, Jańczyk-Ilach, Koblowska, Ciemerych, Grabowska: "Cell cycle regulation of embryonic stem cells and mouse embryonic fibroblasts lacking functional Pax7." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 21, pp. 2931-2942, (2016) (PubMed).

Wehling-Henricks, Li, Lindsey, Wang, Welc, Ramos, Khanlou, Kuro-O, Tidball: "Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy." in: Human molecular genetics, Vol. 25, Issue 12, pp. 2465-2482, (2016) (PubMed).

Akahori, Karmali, Polavarapu, Lyle, Weiss, Shin, Husain, Naqvi, Van Dam, Habib, Choi, King, Pachura, Taylor, Lefer, Finn: "CD163 interacts with TWEAK to regulate tissue regeneration after ischaemic injury." in: Nature communications, Vol. 6, pp. 7792, (2015) (PubMed).

McDonald, Hebert, McLoon: "Sparing of the extraocular muscles in mdx mice with absent or reduced utrophin expression: A life span analysis." in: Neuromuscular disorders : NMD, Vol. 25, Issue 11, pp. 873-87, (2015) (PubMed).

Caldow, Thomas, Dale, Tomkinson, Buckley, Cameron-Smith: "Early myogenic responses to acute exercise before and after resistance training in young men." in: Physiological reports, Vol. 3, Issue 9, (2015) (PubMed).

Details zu PAX7

Target: PAX7 (Paired Box 7 (PAX7))

Andere Bezeichnung: PAX7 (PAX7 Produkte)

Synonyme: PAX7 antikoerper, HUP1 antikoerper, PAX7B antikoerper, RMS2 antikoerper, pax-7 antikoerper, PAX-7 antikoerper, RGD1564360 antikoerper, Pax-7 antikoerper, pax7 antikoerper, pax7c antikoerper, pax7d antikoerper, pax7e antikoerper, paired box 7 antikoerper, paired box protein Pax-7 antikoerper, paired box 7 L homeolog antikoerper, paired box 7a antikoerper, PAX7 antikoerper, pax7.L antikoerper, LOC536229 antikoerper, Pax7 antikoerper, pax7a antikoerper

Hintergrund: PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.
Alias Symbols: FLJ37460, HUP1, PAX7B, RMS2
Protein Interaction Partner: TRIM27, MYOD1, Dlg4, WDR5, ASH2L, HIRA, Ubc,
Protein Size: 520

Molekulargewicht: 57 kDa

Gen-ID: 5081

NCBI Accession: NM_002584, NP_002575

UniProt: P23759